Glutamate Receptors: Finally Fingered in Inherited Epilepsy?
نویسندگان
چکیده
منابع مشابه
Is reading epilepsy inherited?
A patient with primary reading epilepsy is reported. Her daughter has major and minor seizures and shows pattern- and photosensitivity. Both have discharges during reading. The implications of these findings are discussed.
متن کاملIonotropic Glutamate Receptors and their Role in Neurological Diseases
Glutamate is extensively and relatively uniformly distributed in the central nervous system (CNS) and its effects mediated by two distinct groups of receptors including Ionotropic and metabotropic glutamate receptors. Concentration of glutamate in the nervous system is much higher than in other tissues. Glutamate receptors play an important role in synaptic transmission, neural plasticity and n...
متن کاملMolecular basis of inherited epilepsy.
E pilepsy is a common, paroxysmal, and heterogeneous neurological disorder. Many factors, including complex genetic influences, contribute to the pathogenesis of epilepsy. However, several epilepsy syndromes are caused by mutations in single genes (Table). Most epilepsy-associated genes that have been identified within the past 5 years encode ion channels. This review illustrates the progress i...
متن کاملMolecular Basis of an Inherited Epilepsy
Epilepsy is a common neurological condition that reflects neuronal hyperexcitability arising from largely unknown cellular and molecular mechanisms. In generalized epilepsy with febrile seizures plus, an autosomal dominant epilepsy syndrome, mutations in three genes coding for voltage-gated sodium channel alpha or beta1 subunits (SCN1A, SCN2A, SCN1B) and one GABA receptor subunit gene (GABRG2) ...
متن کاملGlutamate and tumor-associated epilepsy
For many patients an unexplained seizure is among the earliest symptoms of a growing primary brain tumor. These tumors originate from glial cells or their progenitors in the brain and are often referred to as glioma. In approximately 30% of patients seizures recur spontaneously giving rise to tumor associated epilepsy [1]. While these fits are generally well controlled by antiepileptic medicati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2007
ISSN: 1535-7597,1535-7511
DOI: 10.1111/j.1535-7511.2007.00191.x